Therapeutic challenges of ESBLS and AmpC beta-lactamase producers in a tertiary care center
نویسندگان
چکیده
منابع مشابه
Evaluation of methods for AmpC beta-lactamase in gram negative clinical isolates from tertiary care hospitals.
The purpose of this study was to simultaneously screen for Extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases in gram negative clinical isolates from four tertiary care hospitals and further to compare two detection methods three-dimensional extraction method and AmpC disk test for AmpC beta-lactamases. A total of 272 isolates were screened for ESBL and AmpC beta-lactamase by mod...
متن کاملDetection of AMPC and ESBL Producers among Enterobacteriaceae in a Tertiary Health Care in, Kano- Nigeria
Resistance to broad spectrum β lactams, mediated by extended spectrum beta lactamase (ESβL) and AmpC βL enzymes is fast spreading in Nigerian hospitals. Production of these enzymes has resulted in treatment failure especially if one of the second or third generation cephalosporins is used. A study was undertaken to determine the prevalence of each enzyme and coproduction of the two enzymes amon...
متن کاملInducible and Plasmid Mediated AmpC Beta-Lactamase among Klebsiella pneumoniae in a Tertiary Care Teaching Hospital of South India
Amp C beta-lactamases are a type of cephalosporinase enzymes belonging to Class C of Ambler’s structural classification, while assigned to group 3 in the functional classification scheme of Bush (Ambler, 1980; Bush et al., 1995). These enzymes can be either chromosomal or plasmid encoded conferring resistance to both oxyimino (cefotaxime, ceftazidime, ceftriaxone) and 7-α methoxy cephalosporins...
متن کاملPenicillin-binding proteins and induction of AmpC beta-lactamase.
In competition assays for radiolabeled penicillin, penicillin-binding proteins (PBPs) 4, 7a, and 7b showed very high affinities for strong inducers of AmpC beta-lactamase. Loss of PBP 4 resulted in diminished inducibility. This suggests that if PBPs are involved in induction of AmpC beta-lactamase, there is probably a redundancy in function among the different PBPs.
متن کاملPhenotypic Identification and Antibiotic Susceptibility Pattern of AmpC beta-Lactamase Producing Escherichia coli and Klebsiella pneumoniae Isolated from Urinary Tract Infections from a Tertiary Care Hospital of Rawalpindi, Pakistan
Introduction: This study is aimed to compare phenotypic test methods and determine antibiotic susceptibility pattern of AmpC beta-lactamase producing uropathogenic Escherichia coli and Klebsiella pneumoniae in clinical isolates. Method: E. coli and K. pneumoniae were identified by standard microbiological procedures. Screening of AmpC beta-lactamase production was done by using cefoxitin disc (...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Journal Armed Forces India
سال: 2013
ISSN: 0377-1237
DOI: 10.1016/j.mjafi.2012.02.001